Caffeine and Adrenal Fatigue. What's the Buzz About?

Can you really get adrenal fatigue from caffeine, or is it a myth?

While you most likely won’t develop adrenal fatigue from caffeine alone, especially not via your morning coffee, caffeine may be affecting your adrenal glands negatively in combination with other challenges in your life. Ultimately, however, if you are a very heavy user of caffeinated beverages, it could be the root cause of your adrenal fatigue.


Before we dive into the nitty gritty, it’s important to remember that the effects of caffeine are notably bio-individual. This largely centers around metabolic rate, which itself has an effect on adrenal fatigue independent of caffeine. You can find out your metabolic rate with a
HTMA (Hair tissue mineral analysis), and you’ll learn much more about metabolic rate in the EnergyRx course


The Adrenal Glands


The Adrenals are a pair of hormone secreting glands that sit atop the kidneys. They are responsible for production of key mood regulating hormones, especially those involved in the stress response, such as cortisol and adrenaline (after which they are named). 


Adrenal fatigue is a name applied to the idea that these glands can, after being stimulated in excess due to a high stress environment (or stimulants such as caffeine) become burned out. This results in less effective hormone regulation which causes a variety of symptoms ranging from anxiety to weight gain to craving salt. The symptom most likely to become apparent is, however, fatigue (in general). If you find yourself asking questions like “Why am I so tired all the time?” adrenal fatigue could be the culprit.


Coffee and Other Caffeine Based Stimulants


Caffeine is the most widely consumed psychoactive drug across the world. It’s popularity is undoubtedly because it has a tangible effect. You can really feel your alertness increasing (perhaps too much in some cases). It’s packaged in many different forms and not all of them are equal. A black coffee is certainly going to be easier going than a double whammy of sugar and caffeine in the form of an energy drink (whatever vitamins they might cram in there to ease the crash). 


There is one caffeinated beverage which really bests all the others, combining calm and focus. That one beverage is Tea, the inclusion of L-theanine as a naturally occurring substance in tea helps to ease the negative side effects of caffeine. I discuss this more in length in my recent article on Tea.


But, if you are really a coffee person there is a way to help take the edge off. Add a little butter to the mix. Not only does it enrich the drink with a creamy flavor and texture, but it also brings an array of fatty acids into the mix which help the caffeine have a delayed release. It's also worth trying to go as organic as possible, both in general and with your coffee beans.



Caffeine and the Adrenal Glands


To understand caffeine's effect on the adrenal glands and how it can lead to or exacerbate adrenal fatigue, we need to look at how caffeine acts in the body.


Caffeine creates neural excitation, and it does this primarily by blocking important receptors involved with hormone and mood regulation (primarily adenosine and benzodiazepine, if you’re interested). 


It is thought that this neural excitation causes the body to think it is under threat. That’s when the brain signals the adrenal glands to secrete hormones that promote further alertness.


It’s well known that adrenaline is raised by caffeine consumption, and cortisol has also been shown to increase significantly in the presence of caffeine, especially when combined with stress or exercise.


There is still a lot we don’t know for certain about caffeine’s mechanisms in the body, but given the evidence supporting increased adrenal activity, it’s sure to have an impact on adrenal health.


Significant amounts of caffeine, if given the opportunity, will tend to cause adrenal fatigue symptoms.


But just how much caffeine is too much caffeine?


Moderating Caffeine to Avoid Adrenal Fatigue


It doesn’t hurt to cut caffeine completely out of the picture. Of course if you’ve been a heavy user it may be wise wean yourself off gradually to avoid harsh withdrawal symptoms.


That said, caffeine is not without its perks, especially for the working professional, so consider making the following alterations to your routines allowing you to more effectively balance usage and dodge fatigued adrenals.


  1. Stay away from sugary caffeinated drinks and opt for more balanced choices such as green tea, or a coffee augmented with butter as previously mentioned.
  2. Only consume caffeine in the morning, the further away from your next snooze the better. - Caffeine’s staying power in the body is very bio-individual, but trying to sleep within 8 hours of a caffeine hit can be practically challenging. Furthermore, in order to steer clear of adrenal fatigue, it’s crucial to give the adrenal glands time to rest and reset.
  3. Employ other wellness practices. While caffeine can cause adrenal fatigue, it’s most likely a combination of factors, so it’s important to maintain good allround wellness practices. 


If you’re interested in really taking back control and reclaiming your energy there is no better place to find the tools to do so than my course, EnergyRx. In order to offset negative effects of caffeine we can take into consideration things such as diet, sleeping habits, exercise habits and more. My course gives you personalized tools to balance your life and wellness again, and that
can mean caffeine without the adrenal burnout (though for some caffeine is just really bad, to the point where it may have to go for them to break free of fatigue).


  4. Take action. If you are suffering from what you think is adrenal fatigue due to caffeine, the most important thing to do is take action. Even if you aren’t totally convinced, consider what's the smallest action you are willing to take right now that might de-incentivize that second coffee this afternoon. 


Perhaps it’s as simple as putting the instant coffee out of reach so that it’s an effort to get to. 


Perhaps it’s as simple as leaving the pocket change that normally goes into the work coffee machine, into the savings jar. 


Go as big as you can (sensibly) but go as small as you have to. 


Just get started on the path of healing. 


If you are interested in learning more about testing for adrenal fatigue or healing your body you are welcome to schedule a free Health Discovery Session with Heidi.



Don't Miss Out!

Heidi Toy Functional Medicine Blog

By Heidi Toy June 14, 2025
Did you know most people didn’t have refrigerators in their homes until well into the 1900’s? It wasn’t even invented for large scale commercial use until the mid 1800’s [1]. So how did people keep their milk cold and make their food last longer? Fermentation. It sounds like a gross concept, because we often associate fermentation with a bad odor, but foods like cheese, yogurt, sauerkraut and pickles are all fermented foods. And those aren’t gross, are they? Well, some might disagree with me about sauerkraut, but that’s beside the point. Fermented foods are digestive aids. Microscopic living organisms in fermented foods help extend the food’s shelf life, enhance flavor, and help the body absorb minerals. These organisms pre-digest the food, getting rid of harmful components, and create more vitamins and enzymes than the food began with. Enzyme-rich foods have many benefits including [2]: Increase digestibility of food we eat Boost immune system Increase alkalinity; neutralizing pH levels Provide a healthy balance of friendly flora in the gut (Learn more about your microbiome in my other blog posts ) Tone the colon and help with elimination Control cravings for unhealthier foods Eliminate toxins and undigested wastes in the body In the “old days,” people use to ferment all kinds of foods through pickling, canning, pasteurization and added salt. Nowadays, however, large scale fermentation has lost many of its nutritious benefits due to the need for speed to get the product on the shelf as fast as possible and as cheap as possible. The only true fermented foods you will find are sauerkraut, kombucha, yogurt and kefir, beans, wine and beer, some meats (such as salami and pastrami), legumes and nuts (such as tofu, soy sauce and miso), sourdough bread, and various kinds of vegetables [3]. Fun facts about sauerkraut: The Germans “stole” it from the Chinese! Sauerkraut (probably not labeled as such for the Chinese, but the same recipe) was one of the main foods for those who built the Great Wall of China. Genghis Khan brought it to Eastern Europe during an invasion. It also contains high levels of vitamin C, and sailors often took it on long journeys to prevent scurvy.
By Heidi Toy May 14, 2025
How can we best keep blood sugar stable? Do what our body is designed to do – use fat for energy. Our species did not survive the Ice Age because of vanilla coffee lattes and cheesecake. Throughout most of our history, we ate a diet that was likely 50-70 percent fat. Look at the old family photo albums, specifically pictures of people in the first half of the 1900s, before we had so many processed foods. You won’t see many fat people--in fact, most look darn skinny. If they lived on the farm, they ate lots of eggs, meat, milk, and vegetables out of their own backyards. “Diet foods” were non-existent. Heart disease was almost non-existent. Our metabolism is designed to work much better with fats better than with sugar. Fats provide the slow and steady fuel our body likes to use for energy. Think of fats as a slow-burning log on the fire. One log (i.e. one meal containing fats) lasts for hours. Starchy carbs, on the flip side, are like kindling. You constantly have to throw more twigs (chips, pasta, bagels) to keep the fire burning. The first step is to know your sugars by reading the labels, and then avoid said sugars as much as possible.
By Heidi Toy May 1, 2025
How Stabilizing Blood Sugar Can Help Put Autoimmune Conditions into Remission and Promote Healing
By Heidi Toy April 14, 2025
Omega-3 and Omega-6 are considered “essential” fatty acids because they cannot be produced by the body--we get them from the food we eat. They are biologically active upon ingestion, which means the body utilizes them right away and cannot store them up for later. They are essential because they help with both inflammatory and anti-inflammatory responses.
By Heidi Toy March 14, 2025
Kill the Candida!
By Heidi Toy March 14, 2025
Hangover or Too Much Yeast?
By Heidi Toy March 10, 2025
Food Cravings Explained: The Hidden Causes of Sugar, Salt, and Carb Cravings (and How to Take Control)
By Heidi Toy February 28, 2025
Why Did I Get Candida and How Can I be Sure?
By Heidi Toy February 17, 2025
Discover How CoQ10 Supports Heart Health, Energy Levels, and More—Especially During Heart Health Month.
Candida yeast overgrowth
By Heidi Toy February 14, 2025
Good Yeast, Bad Yeast
More Posts